Pubblicazioni

I Ricercatori CNR fondatori dell’Azienda, insieme al Team Scientifico, pubblicano articoli scientifici su riviste di settore internazionali, per divulgare la lipidomica di membrana cellulare quale metodo di applicazione, scientificamente validato e efficace, nelle diverse specialità sanitarie.

Tutte le pubblicazioni sono reperibili nei giornali delle società medico – scientifiche e nelle principali banche dati di riferimento per la letteratura scientifica internazionale: PubMed.gov e Reserchgate.net . Di seguito, ordinate per ambito fisio-patologico, sono riportate le nostre pubblicazioni scientifiche.

• LIPIDOMICA APPLICATA IN AMBITO MEDICO DIAGNOSTICO

OMEOSTASI MEMBRANA CELLULARE: 

Ferreri C, Masi A, Sansone A, Giacometti G, Larocca AV, Menounou G, Scanferlato R, Tortorella S, Rota D, Conti M, Deplano S, Louka M, Maranini AR, Salati A, Sunda V, Chatgilialoglu C.
Fatty Acids in Membranes as Homeostatic, Metabolic and Nutritional Biomarkers: Recent Advancements in Analytics and Diagnostics.
Diagnostics (Basel). 2016 Dec 22;7(1):1. doi: 10.3390/diagnostics7010001. PMID: 28025506; PMCID: PMC5373010.

GRAVIDANZA: 

• Bukowiecka-Matusiak M, Burzynska-Pedziwiatr I, Sansone A, Malachowska B, Zurawska-Klis M, Ferreri C, Chatgilialoglu C, Ochedalski T, Cypryk K, Wozniak LA.
  Lipid profile changes in erythrocyte membranes of women with diagnosed GDM.
  PLoS One. 2018 Sep 14;13(9):e0203799. doi: 10.1371/journal.pone.0203799. PMID: 30216387; PMCID: PMC6138398.
• Martini I, Di Domenico EG, Scala R, Caruso F, Ferreri C, Ubaldi FM, Lenzi A, Valensise H.
  Optimization of the viability of stem cells derived from umbilical cord blood after maternal supplementation with DHA during the second or third trimester of pregnancy: study protocol for a randomized controlled trial.
  2014 May 10;15:164. doi: 10.1186/1745-6215-15-164. PMID: 24884585; PMCID: PMC4024184.

LONGEVITA’: 

• Puca AA, Andrew P, Novelli V, Anselmi CV, Somalvico F, Cirillo NA, Chatgilialoglu C, Ferreri C.
  Fatty acid profile of erythrocyte membranes as possible biomarker of longevity.
  Rejuvenation Res. 2008 Feb;11(1):63-72. doi: 10.1089/rej.2007.0566. PMID: 18160025.
• Puca AA, Chatgilialoglu C, Ferreri C.
  Lipid metabolism and diet: possible mechanisms of slow aging.
  Int J Biochem Cell Biol. 2008;40(3):324-33. doi: 10.1016/j.biocel.2007.04.003. Epub 2007 Apr 8. PMID: 17509925.

DERMATITE ATOPICA: 

Ferreri C, Angelini F, Chatgilialoglu C, Dellonte S, Moschese V, Rossi P, Chini L.
Trans fatty acids and atopic eczema/dermatitis syndrome: the relationship with a free radical cis-trans isomerization of membrane lipids.
Lipids. 2005 Jul;40(7):661-7. doi: 10.1007/s11745-005-1428-7. PMID: 16196416.

DISTURBI NEUROLOGICI: 

• Giacometti G, Ferreri C, Sansone A, Chatgilialoglu C, Marzetti C, Spyratou E, Georgakilas AG, Marini M, Abruzzo PM, Bolotta A, Ghezzo A, Minguzzi R, Posar A, Visconti P.
  High predictive values of RBC membrane-based diagnostics by biophotonics in an integrated approach for Autism Spectrum Disorders.
  Sci Rep. 2017 Aug 29;7(1):9854. doi: 10.1038/s41598-017-10361-7. PMID: 28852136; PMCID: PMC5574882.
• Abruzzo PM, Ghezzo A, Bolotta A, Ferreri C, Minguzzi R, Vignini A, Visconti P, Marini M.
  Perspective Biological Markers for Autism Spectrum Disorders: Advantages of the Use of Receiver Operating Characteristic Curves in Evaluating Marker Sensitivity and Specificity.
  Dis Markers. 2015;2015:329607. doi: 10.1155/2015/329607. Epub 2015 Nov 8. PMID: 26648598; PMCID: PMC4655021.
• Ghezzo A, Visconti P, Abruzzo PM, Bolotta A, Ferreri C, Gobbi G, Malisardi G, Manfredini S, Marini M, Nanetti L, Pipitone E, Raffaelli F, Resca F, Vignini A, Mazzanti L.
  Oxidative Stress and Erythrocyte Membrane Alterations in Children with Autism: Correlation with Clinical Features.
  PLoS One. 2013 Jun 19;8(6):e66418. doi: 10.1371/journal.pone.0066418. PMID: 23840462; PMCID: PMC3686873.

NUTRIZIONE PARENTERALE: 

Pironi L, Guidetti M, Verrastro O, Iacona C, Agostini F, Pazzeschi C, Sasdelli AS, Melchiorre M, Ferreri C.
Functional lipidomics in patients on home parenteral nutrition: Effect of lipid emulsions.
World J Gastroenterol. 2017 Jul 7;23(25):4604-4614. doi: 10.3748/wjg.v23.i25.4604. PMID: 28740349; PMCID: PMC5504376.

OBESITA’: 

• Jauregibeitia I, Portune K, Rica I, Tueros I, Velasco O, Grau G, Castaño L, Di Nolfo F, Ferreri C, Arranz S.
  Potential of Erythrocyte Membrane Lipid Profile as a Novel Inflammatory Biomarker to Distinguish Metabolically Healthy Obesity in Children.
  J Pers Med. 2021 Apr 23;11(5):337. doi: 10.3390/jpm11050337. PMID: 33922764.
• Jauregibeitia I, Portune K, Gaztambide S, Rica I, Tueros I, Velasco O, Grau G, Martín A, Castaño L, Larocca AV, Di Nolfo F, Ferreri C, Arranz S.
  Molecular Differences Based on Erythrocyte Fatty Acid Profile to Personalize Dietary Strategies between Adults and Children with Obesity.
  Metabolites. 2021 Jan 8;11(1):43. doi: 10.3390/metabo11010043. PMID: 33435565; PMCID: PMC7827034.
• Jauregibeitia I, Portune K, Rica I, Tueros I, Velasco O, Grau G, Trebolazabala N, Castaño L, Larocca AV, Ferreri C, Arranz S.
  Fatty Acid Profile of Mature Red Blood Cell Membranes and Dietary Intake as a New Approach to Characterize Children with Overweight and Obesity.
  Nutrients. 2020 Nov 10;12(11):3446. doi: 10.3390/nu12113446. PMID: 33182783; PMCID: PMC7696547.
• Sansone A, Tolika E, Louka M, Sunda V, Deplano S, Melchiorre M, Anagnostopoulos D, Chatgilialoglu C, Formisano C, Di Micco R, Faraone Mennella MR, Ferreri C.
  Hexadecenoic Fatty Acid Isomers in Human Blood Lipids and Their Relevance for the Interpretation of Lipidomic Profiles.
  PLoS One. 2016 Apr 5;11(4):e0152378. doi: 0.1371/journal.pone.0152378. PMID: 27045677; PMCID: PMC4821613.

FERTILITA’ MASCHILE: 

Mendeluk GR, Cohen MI, Ferreri C, Chatgilialoglu C.
Nutrition and Reproductive Health: Sperm versus Erythrocyte Lipidomic Profile and ω-3 Intake.
J Nutr Metab. 2015;2015:670526. doi: 10.1155/2015/670526. Epub 2015 Oct 25. PMID: 26583072; PMCID: PMC4637148.

CELIACHIA: 

• Russo F, Chimienti G, Clemente C, Ferreri C, Orlando A, Riezzo G.
  A possible role for ghrelin, leptin, brain-derived neurotrophic factor and docosahexaenoic acid in reducing the quality of life of coeliac disease patients following a gluten-free diet.
  Eur J Nutr. 2017 Mar;56(2):807-818. doi: 10.1007/s00394-015-1128-2. Epub 2015 Dec 21. PMID: 26687809.
• Riezzo G, Ferreri C, Orlando A, Martulli M, D’Attoma B, Russo F.
  Lipidomic analysis of fatty acids in erythrocytes of coeliac patients before and after a gluten-free diet intervention: a comparison with healthy subjects.
  Br J Nutr. 2014 Dec 14;112(11):1787-96. doi: 10.1017/S0007114514002815. Epub 2014 Sep 30. PMID: 25266177.

ONCOLOGIA: 

• Amézaga J, Ugartemendia G, Larraioz A, Bretaña N, Iruretagoyena A, Camba J, Urruticoechea A, Ferreri C, Tueros I.
  Altered Levels of Desaturation and ω-6 Fatty Acids in Breast Cancer Patients’ Red Blood Cell Membranes.
  Metabolites. 2020 Nov 17;10(11):469. doi: 10.3390/metabo10110469. PMID: 33212920; PMCID: PMC7698438.
• Ferreri C, Sansone A, Ferreri R, Amézaga J, Tueros I.
  Fatty Acids and Membrane Lipidomics in Oncology: A Cross-Road of Nutritional, Signaling and Metabolic Pathways.
  Metabolites. 2020 Aug 25;10(9):345. doi: 10.3390/metabo10090345. PMID: 32854444; PMCID: PMC7570129.
• Amézaga J, Arranz S, Urruticoechea A, Ugartemendia G, Larraioz A, Louka M, Uriarte M, Ferreri C, Tueros I.
  Altered Red Blood Cell Membrane Fatty Acid Profile in Cancer Patients.
  Nutrients. 2018 Dec 1;10(12):1853. doi: 10.3390/nu10121853. PMID: 30513730; PMCID: PMC6315925.

FIBRILLAZIONE ATRIALE: 

Viviani Anselmi C, Ferreri C, Novelli V, Roncarati R, Bronzini R, Marchese G, Somalvico F, Condorelli G, Montenero AS, Puca AA.
Fatty acid percentage in erythrocyte membranes of atrial flutter/fibrillation patients and controls.
J Interv Card Electrophysiol. 2010 Mar;27(2):95-9. doi: 10.1007/s10840-009-9466-8. Epub 2010 Feb 17. PMID: 20162444.

PATOLOGIE EPATICHE: 

Svegliati-Baroni G, Pierantonelli I, Torquato P, Marinelli R, Ferreri C, Chatgilialoglu C, Bartolini D, Galli F.
Lipidomic biomarkers and mechanisms of lipotoxicity in non-alcoholic fatty liver disease.
Free Radic Biol Med. 2019 Nov 20;144:293-309. doi: 10.1016/j.freeradbiomed.2019.05.029. Epub 2019 May 29. PMID: 31152791.

• LIPIDOMICA APPLICATA IN AMBITO BIOLOGICO

CELLULE UMANE: 

• Krokidis MG, Parlanti E, D’Errico M, Pascucci B, Pino A, Alimonti A, Pietraforte D, Masi A, Ferreri C, Chatgilialoglu C.
  Purine DNA Lesions at Different Oxygen Concentration in DNA Repair-Impaired Human Cells (EUE-siXPA).
  Cells. 2019 Nov 1;8(11):1377. doi: 10.3390/cells8111377. PMID: 31683970; PMCID: PMC6912421.
• Bianchi AR, Ferreri C, Ruggiero S, Deplano S, Sunda V, Galloro G, Formisano C, Mennella MR.
  Automodification of PARP and fatty acid-based membrane lipidome as a promising integrated biomarker panel in molecular medicine.
  Biomark Med. 2016;10(3):229-42. doi: 10.2217/bmm.16.3. Epub 2016 Feb 9. PMID: 26860237.

CELLULE UMANE – ONCOLOGIA: 

• Ferreri C, Sansone A, Buratta S, Urbanelli L, Costanzi E, Emiliani C, Chatgilialoglu C.
  The n-10 Fatty Acids Family in the Lipidome of Human Prostatic Adenocarcinoma Cell Membranes and Extracellular Vesicles.
  Cancers (Basel). 2020 Apr 7;12(4):900. doi: 10.3390/cancers12040900. PMID: 32272739; PMCID: PMC7226157.
• Scanferlato R, Bortolotti M, Sansone A, Chatgilialoglu C, Polito L, De Spirito M, Maulucci G, Bolognesi A, Ferreri C.
  Hexadecenoic Fatty Acid Positional Isomers and De Novo PUFA Synthesis in Colon Cancer Cells.
  Int J Mol Sci. 2019 Feb 15;20(4):832. doi: 10.3390/ijms20040832. PMID: 30769921; PMCID: PMC6412212.
• Chatgilialoglu C, Ferreri C, Geacintov NE, Krokidis MG, Liu Y, Masi A, Shafirovich V, Terzidis MA, Tsegay PS.
  5′,8-Cyclopurine Lesions in DNA Damage: Chemical, Analytical, Biological, and Diagnostic Significance.
  Cells. 2019 May 28;8(6):513. doi: 10.3390/cells8060513. PMID: 31141888; PMCID: PMC6628319.

CELLULE MURINE: 

• Krokidis MG, Louka M, Efthimiadou EK, Zervou SK, Papadopoulos K, Hiskia A, Ferreri C, Chatgilialoglu C.
  Membrane Lipidome Reorganization and Accumulation of Tissue DNA Lesions in Tumor-Bearing Mice: An Exploratory Study.
  Cancers (Basel). 2019 Apr 4;11(4):480. doi: 10.3390/cancers11040480. PMID: 30987375; PMCID: PMC6520748.
• Maulucci G, Cohen O, Daniel B, Sansone A, Petropoulou PI, Filou S, Spyridonidis A, Pani G, De Spirito M, Chatgilialoglu C, Ferreri C, Kypreos KE, Sasson S.
  Fatty acid-related modulations of membrane fluidity in cells: detection and implications.
  Free Radic Res. 2016 Nov;50(sup1):S40-S50. doi: 10.1080/10715762.2016.1231403. Epub 2016 Oct 25. PMID: 27593084.

• LIPIDOMICA APPLICATA IN AMBITO CHIMICO-FARMACEUTICO

ACIDI GRASSI TRANS: 

• Vetica F, Sansone A, Meliota C, Batani G, Roberti M, Chatgilialoglu C, Ferreri C.
  Free-Radical-Mediated Formation of Trans-Cardiolipin Isomers, Analytical Approaches for Lipidomics and Consequences of the Structural Organization of Membranes.
  Biomolecules. 2020 Aug 15;10(8):1189. doi: 10.3390/biom10081189. PMID: 32824246; PMCID: PMC7465319.
• Menounou G, Giacometti G, Scanferlato R, Dambruoso P, Sansone A, Tueros I, Amézaga J, Chatgilialoglu C, Ferreri C.
  Trans Lipid Library: Synthesis of Docosahexaenoic Acid (DHA) Monotrans Isomers and Regioisomer Identification in DHA-Containing Supplements.
  Chem Res Toxicol. 2018 Mar 19;31(3):191-200. doi: 10.1021/acs.chemrestox.8b00021. Epub 2018 Mar 6. PMID: 29485870.
• Giacometti G, Marini M, Papadopoulos K, Ferreri C, Chatgilialoglu C.
  Trans-Double Bond-Containing Liposomes as Potential Carriers for Drug Delivery.
  Molecules. 2017 Nov 28;22(12):2082. doi: 10.3390/molecules22122082. PMID: 29182583; PMCID: PMC6149667.
• Cort A, Ozben T, Sansone A, Barata-Vallejo S, Chatgilialoglu C, Ferreri C.
  Bleomycin-induced trans lipid formation in cell membranes and in liposome models.
  Org Biomol Chem. 2015 Jan 28;13(4):1100-5. doi: 10.1039/c4ob01924e. Epub 2014 Nov 24. PMID: 25417813.
• Ferreri C, Panagiotaki M, Chatgilialoglu C.
  Trans fatty acids in membranes: the free radical path.
  Mol Biotechnol. 2007 Sep;37(1):19-25. doi: 10.1007/s12033-007-0054-9. PMID: 17914159.
• Ferreri C, Chatgilialoglu C.
  Geometrical trans lipid isomers: a new target for lipidomics.
  Chembiochem. 2005 Oct;6(10):1722-34. doi: 10.1002/cbic.200500109. PMID: 16196019.
• Ferreri C, Chatgilialoglu C.
  Trans lipids: the free radical path.
  Acc Chem Res. 2005 Jun;38(6):441-8. doi: 10.1021/ar0400847. PMID: 15966710.

• LIPIDOMICA APPLICATA IN AMBITO VETERINARIO

Prasinou P, Crisi PE, Chatgilialoglu C, Di Tommaso M, Sansone A, Gramenzi A, Belà B, De Santis F, Boari A, Ferreri C.
The Erythrocyte Membrane Lipidome of Healthy Dogs: Creating a Benchmark of Fatty Acid Distribution and Interval Values.
Front Vet Sci. 2020 Aug 21;7:502. doi: 10.3389/fvets.2020.00502. PMID: 32974399; PMCID: PMC7472600.